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Thrombosis of the Cerebral Veins and Sinuses

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  • Jan Stam, M.D., Ph.D.

Thrombosis of the cerebral veins and sinuses affects mainly young adults and children. This potentially disabling or fatal condition is usually not diagnosed until a week after the onset of symptoms. This review article describes the clinical presentations of the disorder such as those that occur after a head injury or lumbar puncture. Therapeutic options include anticoagulation, thrombolysis, and measures to control intracranial hypertension.

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Funding and Disclosures

I am indebted to Marinus Vermeulen and Wouter Wieling for their comments on early versions of the manuscript, to Dirk Troost for providing Figure 2, and to Charles B.L.M. Majoie for his help with Figures 3, 4, and 5.

Author Affiliations

From the Department of Neurology, Academic Medical Center, University of Amsterdam, Amsterdam.

Address reprint requests to Dr. Stam at the Department of Neurology, Academic Medical Center, University of Amsterdam, P.O. Box 22700, 1100 DE Amsterdam, the Netherlands, or at .

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