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Review ArticleDrug TherapyFree Preview

Immunosuppressive Drugs for Kidney Transplantation

  • Philip F. Halloran, M.D., Ph.D.

Suppression of allograft rejection is central to successful organ transplantation; thus, immunosuppressive agents are crucial for successful allograft function. Immunosuppressive drugs are used for induction (intense immunosuppression in the initial days after transplantation), maintenance, and reversal of established rejection. This review considers the use of immunosuppressive drugs in organ transplantation, focusing on renal transplantation.

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Funding and Disclosures

Dr. Halloran reports having received lecture fees from Roche and Fujisawa.

I am indebted to Dr. Deborah James for her help in preparing the text and tables; to Drs. Karl Brinker, Arthur Matas, Sita Gourishankar, and Attapong Vongwiwatana for reviewing the manuscript; and to Pam Publicover for her assistance in the preparation of the manuscript.

Author Affiliations

From the Division of Nephrology and Transplantation Immunology, University of Alberta, Edmonton, Canada.

Address reprint requests to Dr. Halloran at 250 Heritage Medical Research Centre, Edmonton, AB T6G 2S2, Canada, or at .

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