Disseminated Intravascular Coagulopathy

Figure 1. A 34-year-old man with the acquired immunodeficiency syndrome, hemoglobin SC chronic hemolytic anemia, and recurrent episodes of pneumonia due to gram-negative bacteria, cryptococcus, and most recently, aspergillus was treated with amphotericin B. Bilateral diffuse pneumonia, gram-negative septicemia with thrombocytopenia and refractory hypotension, and acute oliguric renal failure resulted in his admission to the hospital three days before he died. Pseudomonas aeruginosa, Klebsiella pneumoniae, and aspergillus species were isolated from antemortem sputum cultures, and the first two organisms were also identified in antemortem blood cultures and postmortem lung cultures. The patient's peripheral-blood platelet count decreased from 228,000 to 9000 . . .

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