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Barnyard Microbes and Childhood Asthma

List of authors.
  • James E. Gern, M.D.

It is easy to imagine why children who are raised on farms might grow up healthy: there is plenty of fresh air, exercise, and exposure to sunlight. In fact, studies from Europe, North America, and Australasia provide convincing evidence that allergic diseases and asthma are less likely to develop in children who live on farms than in those who do not.1 Surprisingly, according to the findings of Ege and colleagues in this issue of the Journal, 2 the mechanism responsible for these health effects appears not to be related to clean living but instead to bacteria and fungi from the barnyard. . . .

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Funding and Disclosures

Disclosure forms provided by the author are available with the full text of this article at NEJM.org.

Author Affiliations

From the Departments of Pediatrics and Medicine, University of Wisconsin School of Medicine and Public Health, Madison.