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Clinical PracticeFree Preview

Uncomplicated Urinary Tract Infection

List of authors.
  • Thomas M. Hooton, M.D.

Nitrofurantoin, trimethoprim–sulfamethoxazole, fosfomycin, and pivmecillinam are considered first-line agents for cystitis. Fluoroquinolones should not be routine first-line choices for cystitis, although they are first-line empirical therapy for pyelonephritis.

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Funding and Disclosures

Dr. Hooton reports receiving consulting fees from Pinnacle Pharmaceuticals, Pfizer, and Alita Pharmaceuticals. No other potential conflict of interest relevant to this article was reported.

Disclosure forms provided by the author are available with the full text of this article at NEJM.org.

This article (10.1056/NEJMcp1104429) was updated on March 15, 2012, at NEJM.org.

Author Affiliations

From the University of Miami, Miami.

Address reprint requests to Dr. Hooton at the Department of Medicine, University of Miami Miller School of Medicine, Clinical Research Bldg., 1120 NW 14th St., Suite 310G, Miami, FL 33136, or at .

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