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A correction has been published 1

Clinical PracticeFree Preview

Prolactinomas

List of authors.
  • Anne Klibanski, M.D.

A 42-year-old man presents with decreased libido, erectile dysfunction, and headaches. He reports no weight change, gynecomastia, fatigue, or other symptoms. He takes no medications. Testicular size is decreased. His prolactin level is 648 μg per liter (normal value, <15). Magnetic resonance imaging reveals a sellar mass (2.5 by 1.5 by 2.0 cm) that is 5 mm below the optic chiasm and that extends bilaterally into the cavernous sinuses. What are the diagnostic and therapeutic considerations?

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Funding and Disclosures

Dr. Klibanski reports receiving grant support from Novartis and Pfizer.

No other potential conflict of interest relevant to this article was reported.

This article (10.1056/NEJMcp0912025) was updated on June 2, 2010, at NEJM.org.

An audio version of this article is available at NEJM.org.

Author Affiliations

From the Neuroendocrine Unit, Massachusetts General Hospital, and Harvard Medical School — both in Boston.

Address reprint requests to Dr. Klibanski at the Neuroendocrine Unit, Massachusetts General Hospital, 55 Fruit St., BUL457B, Boston, MA 02114, or at .

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