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Clinical Implications of Basic ResearchFree Preview

The Genetic Archaeology of Influenza

  • Daniel F. Hoft, M.D., Ph.D.,
  • and Robert B. Belshe, M.D.

A recent study suggests that the hemagglutinin protein of the 1918–1919 influenza (Spanish influenza) pandemic led to the hemorrhagic pneumonia and hence a high level of mortality associated with Spanish influenza. This finding, together with the epidemiology of Spanish flu, has implications for response to future pandemics.

Author Affiliations

From the Division of Infectious Disease and Immunology, Department of Internal Medicine and Molecular Microbiology, Saint Louis University, St. Louis.

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