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Priming with Whole-Cell versus Acellular Pertussis Vaccine

About 15 years ago, as part of the pediatric series of vaccines for diphtheria, tetanus, and pertussis, a transition from whole-cell to acellular pertussis vaccine occurred. In this report, investigators from Oregon explore the potential effect of this vaccine switch on subsequent pertussis disease.

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Juventila Liko, M.D., M.P.H.
Steve G. Robison, B.S.
Paul R. Cieslak, M.D.
Oregon Health Authority, Portland, OR

Funding and Disclosures

Supported by Cooperative Agreement number 1U50CK000197 from the Centers for Disease Control and Prevention.

Disclosure forms provided by the authors are available with the full text of this letter at NEJM.org.

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