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How Contagious Are Common Respiratory Tract Infections?

To the Editor: Musher (March 27 issue)1 points out that adenoviruses have caused large outbreaks among military recruits, but additional comment is needed. Adenoviruses do cause epidemics in young adults.25 Before vaccination, adenovirus-associated acute respiratory disease affected up to 10 percent of recruits and was responsible for nearly 70 percent of respiratory disease.3 Implementation of an adenovirus-vaccination policy in the military in 1971 resulted in a dramatic reduction in the occurrence of adenovirus-associated acute respiratory disease, but the manufacturer stopped producing the vaccines in 1995.3 Since then, a substantial number of outbreaks of adenovirus infection have occurred.35 Administration . . .

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Joshua D. Hartzell, M.D.
Charles N. Oster, M.D.
Walter Reed Army Medical Center, Washington, DC 20307

Joel C. Gaydos, M.D., M.P.H.
Department of Defense, Global Emerging Infections Surveillance System, Silver Spring, MD 20910

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