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Eating Disorders

  • Anne E. Becker, M.D., Ph.D.,
  • Steven K. Grinspoon, M.D.,
  • Anne Klibanski, M.D.,
  • and David B. Herzog, M.D.

This article has no abstract; the first 100 words appear below.

Eating disorders affect an estimated 5 million Americans every year. These illnesses — anorexia nervosa, bulimia nervosa, binge-eating disorder, and their variants — are characterized by a serious disturbance in eating, such as restriction of intake or bingeing, as well as distress or excessive concern about body shape or body weight. In addition to their effects on psychological well-being, they have a potentially devastating effect on health through the physiologic sequelae of altered nutritional status or purging. The mortality rate associated with anorexia nervosa alone, at 0.56 percent per year, is more than 12 times as high as the mortality . . .

Funding and Disclosures

Supported in part by grants from the National Institutes of Health (5R01 MH38333, R01 DK5265, and 5M01 RR01066) and by the Rubenstein Foundation.

We are indebted to Dr. Jennifer Rathbun for helpful comments on previous drafts of the manuscript.

Author Affiliations

From the Departments of Psychiatry (A.E.B., D.B.H.), Pediatrics (D.B.H.), and Medicine (S.K.G., A.K.), Massachusetts General Hospital and Harvard Medical School; and the Harvard Eating Disorders Center, Harvard Medical School (A.E.B., D.B.H.) — all in Boston.

Address reprint requests to Dr. Herzog at the Harvard Eating Disorders Center, 356 Boylston St., Boston, MA 02116, or at .

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