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Review ArticleMedical ProgressFree Preview

Lung Transplantation

List of authors.
  • Selim M. Arcasoy, M.D.,
  • and Robert M. Kotloff, M.D.

Since the performance of the first successful lung transplantation nearly two decades ago, the procedure has gained widespread acceptance as a therapeutic option for a diverse array of lung diseases. For patients with severe functional impairment and limited life expectancy, lung transplantation offers the possibility of a markedly improved quality of life and longer survival. Nonetheless, complications are frequent and result in constraints on long-term preservation of graft function and patient survival. This article will review the current status of lung transplantation, with particular attention to the selection of patients, achievable outcomes, and complications.Recent TrendsAfter the initial technical . . .

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Funding and Disclosures

Supported in part by the Craig and Elaine Dobbin Pulmonary Research Fund of the University of Pennsylvania Medical Center.

We are indebted to John Hansen-Flaschen, M.D., for his critical review of the manuscript.

Author Affiliations

From the Program for Advanced Lung Disease and Lung Transplantation, Pulmonary and Critical Care Division, University of Pennsylvania Medical Center, Philadelphia.

Address reprint requests to Dr. Kotloff at the Pulmonary and Critical Care Division, University of Pennsylvania Medical Center, 3400 Spruce St., Philadelphia, PA 19104, or at .

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