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Review ArticleMedical ProgressFree Preview

Cutaneous Melanoma

List of authors.
  • Howard K. Koh, M.D.

CUTANEOUS melanoma has become a common form of cancer.1 Decades of steady increases in the incidence and mortality rates of cutaneous malignant melanoma have sparked global interest in the nature of this cancer.2 3 4 5 6 Recent research has advanced our understanding of cutaneous melanoma and its biology, natural history, and treatment.7 This article reviews the current state of knowledge of melanoma and outlines approaches to treatment and control.EpidemiologyThe incidence of melanoma continues to rise throughout the world (Table 1). In the United States, the incidence of melanoma has almost tripled in the past four decades, growing faster than that of . . .

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Funding and Disclosures

Supported in part by the Herman and Teddie Topoff Melanoma Research Fund at the Boston University School of Medicine and a grant (5K07–CA01380–03) from the National Institutes of Health. Dr. Koh is the recipient of the Preventive Oncology Academic Award from the National Cancer Institute.

I am indebted to Alan Geller, M.P.H., and Mary Beth Mercer, M.P.H., for their invaluable assistance; to Drs. Bob Lew, Don Miller, Barbara Gilchrest, Amal Kurban, Gary Rogers, Jag Bhawan, Mina Yaar, Robert Beazley, Paul Hesketh, Adele Green, and Harry Goldsmith for their thoughtful comments on this manuscript; to Cynthia Barber, M.P.H., for her careful review of this article; and to Dr. Claudia Arrigg for unending encouragement and support.

Author Affiliations

From the Departments of Dermatology and Medicine and the Section of Epidemiology and Biostatistics, Boston University Schools of Medicine and Public Health, and the Skin Oncology Program, University Hospital, all in Boston. Address reprint requests to Dr. Koh at the Boston University Medical Center, 88 E. Newton St., Boston, MA 02118.