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Yogurt — An Autodigesting Source of Lactose

List of authors.
  • Joseph C. Kolars, M.D.,
  • Michael D. Levitt, M.D.,
  • Mostafa Aouji, D.A.G.,
  • and Dennis A. Savaiano, Ph.D.

Abstract

Large quantities of yogurt are consumed by some lactase-deficient population groups. We used breath hydrogen measurements to determine whether lactase-deficient subjects absorbed lactose in yogurt better than lactose in milk. Ingestion of 18 g of lactose in yogurt resulted in only about one third as much hydrogen excretion as a similar load of lactose in milk or water, indicating a much better absorption of lactose in yogurt. Ingestion of yogurt also resulted in fewer reports of diarrhea or flatulence than did a similar quantity of lactose ingested in milk or a water solution. The enhanced absorption of lactose in yogurt appeared to result from the intraintestinal digestion of lactose by lactase released from the yogurt organisms. This autodigesting feature makes yogurt a well-tolerated source of milk for lactase-deficient persons and may explain the widespread consumption of yogurt by lactase-deficient population groups. (N Engl J Med 1984; 310:1–3.)

Funding and Disclosures

Supported by grants from the Veterans Administration and the National Institutes of Health (5 R01 AM 13309–15).

Author Affiliations

From the Research Service, Veterans Administration Medical Center, and the Departments of Medicine and Food Science and Nutrition, University of Minnesota, Minneapolis and St. Paul. Address reprint requests to Dr. Levitt at ACOS for Research/151, Veterans Administration Medical Center, 54th St. and 48th Ave. S., Minneapolis, MN 55417.

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