Angio-Immunoblastic (Immunoblastic) Lymphadenopathy

The clinical picture of generalized lymphadenopathy with or without hepatosplenomegaly may be seen in a variety of diseases. In such cases, if the clinical laboratory data are not diagnostic of a specific entity, an excisional lymph-node biopsy must be performed without delay. One of the most important problems faced by the pathologist is to distinguish between malignant and reactive proliferations of the lymphoreticular tissue. This differential diagnosis may be complicated by the fact that the lymphoid tissue of man and animals reacts intensely to a variety of infectious and other antigenic stimuli, and the resulting proliferative process may and often . . .