Treatment of Myasthenia Gravis

THE therapy of myasthenia gravis is one of the more challenging but often also one of the most rewarding forms of drug therapy encountered by the physician. Myasthenia is a chronic disease characterized by skeletal-muscle weakness that may range in severity from slight depression of maximal strength to complete motor failure. These extremes of functional impairment may be seen at different times in the same patient. Any muscle may be affected. Thus, the functional impairment ranges from slight ptosis to complete respiratory failure. The course of the disease is highly variable, and prognosis is uncertain. The goal of drug therapy . . .