Hepatitis Associated with Myocarditis — Unusual Manifestation of Infection with Coxsackie Virus Group B, Type 3

INFECTION with Coxsackie virus Group B has been shown to cause varying combinations of pleuritis, meningitis, encephalitis, pericarditis, myocarditis, epididymitis, orchitis and pancreatitis.^{1 2 3} It may result in severe illness and death in newborn and infant children. The uncomplicated disease runs a more benign course in adults.Despite the demonstratedly widespread organ involvement in this disease, associated hepatitis in adult patients has been suggested in only 2 previously published reports.^{4 , 5} Furthermore, there has been no published report of the pathologic changes occurring in the livers of adult patients with proved infection with Coxsackie virus Group B.Recently, a nineteen-year-old female patient, . . .