Skip to main content
Device Global Header

Subscribe
or Renew

Advanced Search

This article is available to subscribers. Subscribe now. Already have an account? Sign in

Medical ProgressFree PreviewArchive

Clinical Use of Lactic Dehydrogenase

List of authors.
  • Russell J. Erickson, M.D.‡,
  • and Daniel R. Morales‡

LymphomasThe largest study of SLDH in this group of neoplasms is again that of Bierman and his co-workers.25 Five of the 16 patients with normal values in their series were under treatment when assayed. Studying a smaller population, we41 corroborated their data. West and his associates32 showed a lower percentage of elevations in their series, and 3 other groups listed in Table 122,28,38 demonstrated a total of only 6 elevated values in 17 such patients. Cellular infiltration of the liver has been observed in patients with lymphomas who had high SLDH.32 This could indicate a basic mechanism for SLDH . . .

Funding and Disclosures

* From the Cancer Research Institute, University of California School of Medicine.

Supported by the Al Holman Memorial Cancer Foundation Scholarship Fund, and by Public Health Service grants for undergraduate cancer training (CT 493) and for chemotherapy and pathophysiology in clinical cancer (CY 3422).

We are indebted to Dr. David A. Wood, director of the Cancer Research Institute of the University of California School of Medicine, whose encouragement and support have made this work possible, and to Dr. Jean C. Sabine for her excellent criticisms and encouragement during the preparation of this paper.

Author Affiliations

SAN FRANCISCO

† Intern, Department of Pediatrics, University of California School of Medicine.

‡ Ph.D. candidate, Department of Biochemistry, University of California School of Medicine.

Print Subscriber? Activate your online access.