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Toxic Encephalopathy Apparently Related to the Use of an Insect Repellent

List of authors.
  • Joyce Gryboski, M.D.,
  • David Weinstein, M.B., Ch.B.,
  • and Nelson K. Ordway, M.D.§

IN view of the popular use of insect repellents during the summer months, it is the purpose of this report to describe a case of toxic encephalopathy related to the use of the product, "OFF." There are no previously reported cases in human beings.Case ReportA 3 1/2-year-old girl was admitted to the Pediatric Service of the Grace–New Haven Community Hospital at 4 p.m. on July 26, 1959, with the chief complaint of "shaking and crying spells" of 1 day's duration. She had been well until the previous day, when at 9 a.m. she was found on the floor. . . .

Funding and Disclosures

* From the Department of Pediatrics, Yale University School of Medicine, and the Grace–New Haven Community Hospital.

We are indebted to Dr. Sidney Hurwitz, who referred this patient to our hospital, and to Dr. Arthur Blank, technical director of the Connecticut Poison Information Center, for providing us with the toxicologic information on the product.

Author Affiliations

NEW HAVEN, CONNECTICUT

†Resident, Department of Pediatrics, University Service, Grace–New Haven Community Hospital.

‡Assistant resident. Department of Pediatrics, University Service, Grace–New Haven Community Hospital.

§Professor of pediatrics, Yale University School of Medicine; chief of pediatrics, University Service, Grace–New Haven Community Hospital.

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