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Review Article

The Human Intestinal Microbiome in Health and Disease

List of authors.
  • Susan V. Lynch, Ph.D.,
  • and Oluf Pedersen, M.D., D.M.Sc.

The large majority of studies on the role of the microbiome in the pathogenesis of disease are correlative and preclinical; several have influenced clinical practice.

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Funding and Disclosures

Disclosure forms provided by the authors are available with the full text of this article at NEJM.org.

Author Affiliations

From the Division of Gastroenterology, Department of Medicine, University of California, San Francisco, San Francisco (S.V.L.); and the Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Science, University of Copenhagen, Copenhagen (O.P.).

Address reprint requests to Dr. Lynch at the Division of Gastroenterology, Department of Medicine, University of California, San Francisco, 513 Parnassus Ave., S357D, San Francisco, CA 94143, or at ; or to Dr. Pedersen at the Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 1, 1st floor, DIKU, 2100 Copenhagen, Denmark, or at .

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