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Review Article

Adverse Health Effects of Marijuana Use

  • Nora D. Volkow, M.D.,
  • Ruben D. Baler, Ph.D.,
  • Wilson M. Compton, M.D.,
  • and Susan R.B. Weiss, Ph.D.

As marijuana use becomes legal in some states, the dominant public opinion is that marijuana is a harmless source of mood alteration. Although the harms associated with marijuana use have not been well studied, enough information is available to cause concern.

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Funding and Disclosures

Disclosure forms provided by the authors are available with the full text of this article at NEJM.org.

No potential conflict of interest relevant to this article was reported.

Author Affiliations

From the National Institute on Drug Abuse, National Institutes of Health, Bethesda, MD.

Address reprint requests to Dr. Volkow at the National Institute on Drug Abuse, 6001 Executive Blvd., Rm. 5274, Bethesda, MD 20892, or at .

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