The Promise and Perils of Antioxidants for Cancer Patients
List of authors.
Navdeep S. Chandel, Ph.D.,
and David A. Tuveson, M.D., Ph.D.
It has been proposed that reactive oxygen species (ROS) cause mutations, and thus cancer, and that antioxidants counter this effect, but studies suggest that antioxidants do not prevent cancer and may accelerate it. These findings may be due to the cellular location of ROS targeted by antioxidants.
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Author Affiliations
From the Feinberg School of Medicine, Northwestern University, Chicago (N.S.C.); and the Lustgarten Foundation Laboratory at Cold Spring Harbor Laboratory, Cold Spring Harbor, NY (D.A.T.).