This article is available to subscribers. Subscribe now. Already have an account? Sign in

Review ArticleMechanisms of Disease

Intrauterine Infection and Preterm Delivery

List of authors.
  • Robert L. Goldenberg, M.D.,
  • John C. Hauth, M.D.,
  • and William W. Andrews, Ph.D., M.D.

Preterm delivery is the chief problem in obstetrics today, accounting for 70 percent of perinatal mortality and nearly half of long-term neurologic morbidity.1,2 Approximately 10 percent of all births are preterm, but most of the serious illness and death is concentrated in the 1 to 2 percent of infants who are born at less than 32 weeks of gestation and who weigh less than 1500 g. Approximately 20 percent of preterm births are the result of a physician's decision to bring about delivery for maternal or fetal indications, and the remainder follow the spontaneous onset of labor or rupture . . .

Continue reading this article

Select an option below:

Create your account to get 2 free subscriber-only articles each month.

Get Free Access Now Subscribe For Full Access

Already have an account?

Sign In

Print subscriber?

Activate your online access.

Author Affiliations

From the Department of Obstetrics and Gynecology and the Center for Research on Women's Health, University of Alabama at Birmingham, Birmingham.

Address reprint requests to Dr. Goldenberg at the Department of Obstetrics and Gynecology, University of Alabama at Birmingham, 618 S. 20th St., OHB 560, Birmingham, AL 35233-7333, or at .

Print Subscriber? Activate your online access.