This article is available to subscribers. Subscribe now. Already have an account? Sign in

A correction has been published 1

Review ArticleDrug Therapy

Drugs and Surgery in the Prevention of Ischemic Stroke

List of authors.
  • Henry J.M. Barnett, M.D.,
  • Michael Eliasziw, Ph.D.,
  • and Heather E. Meldrum, B.A.

Ischemic and hemorrhagic strokes are among the principal causes of death and disability in older people, although the incidence of such strokes is lower than in the past.1,2 Control of blood pressure, decreased cigarette smoking, and possibly altered dietary habits are among the important but unconfirmed reasons proposed for this decline.35 This review addresses the antithrombotic and surgical measures to prevent ischemic stroke that have been rigorously evaluated in randomized clinical trials.Use of Anticoagulant Agents to Prevent Ischemic StrokeSince the introduction of anticoagulant agents 50 years ago, their use has varied widely, which is to be . . .

Continue reading this article

Select an option below:

Create your account to get 2 free subscriber-only articles each month.

Get Free Access Now Subscribe For Full Access

Already have an account?

Sign In

Print subscriber?

Activate your online access.

Funding and Disclosures

Supported by a grant (R01-NS-24456) from the National Institute of Neurological Disorders and Stroke.

Author Affiliations

From the Departments of Clinical Neurological Sciences (H.J.M.B.) and Epidemiology and Biostatistics (M.E.), University of Western Ontario, and the John P. Robarts Research Institute (H.J.M.B., M.E., H.E.M.), both in London, Ont., Canada.

Address reprint requests to Dr. Barnett at the Robarts Research Institute, 100 Perth Dr., P.O. Box 5015, London, ON N6A 5K8, Canada.

Print Subscriber? Activate your online access.