Lung function was measured in firefighters and emergency-medical-service workers who responded to the collapse of the World Trade Center towers in New York on September 11, 2001. There was initial marked loss in lung-function measures without substantial recovery during the following 7 years.

In this randomized trial comparing cisplatin plus gemcitabine with gemcitabine alone for the treatment of biliary tract cancer, overall survival and progression-free survival were improved with the use of cisplatin plus gemcitabine. Adverse events were similar in the two groups.

It has been hypothesized that oxidative stress may underlie the development of preeclampsia. In this large, multicenter, randomized, double-blind trial involving low-risk, nulliparous women, supplementation with 1000 mg of vitamin C and 400 IU of vitamin E, beginning in the 9th to 16th week of pregnancy, did not reduce the rates of adverse maternal or perinatal outcomes related to pregnancy-associated hypertension.

In this randomized trial of patients infected with hepatitis C virus genotype 1 in whom a sustained virologic response was not achieved after initial therapy, patients retreated with peginterferon alfa-2a and ribavirin combined with telaprevir were more likely to have a sustained response than patients retreated with peginterferon alfa-2a and ribavirin alone.