To the Editor: The study by Shrestha et al. (March 1 issue),¹ which evaluated a vaccine for hepatitis E virus (HEV), represents a major advance but continues to raise ethical concerns. The trial of the HEV recombinant protein (rHEV) vaccine, conducted by ...

To the Editor: The Special Article by Landon and colleagues (March 1 issue)¹ on improving the management of chronic disease at community health centers illustrates the importance of identifying appropriate outcomes when measuring the effectiveness of ...

To the Editor: In his review article on amiodarone for atrial fibrillation, Zimetbaum (March 1 issue)¹ did not mention that there are two forms of amiodarone-induced thyrotoxicosis (AIT) — an important distinction that has a major influence on subsequent ...

To the Editor: The Sounding Board article by Hanto on the ethical challenges posed by solicitation of organ donation (March 8 issue)¹ does not clearly distinguish between directed donation and solicitation. Although effective solicitation requires ...

To the Editor: The Clinical Problem-Solving article by Safdar et al. (March 1 issue)¹ concerns an immunocompromised woman who received the diagnosis of pulmonary nocardiosis. The authors recommended that if the patient still required immunosuppression ...

To the Editor: The mobile aortic thrombus described by Adam et al. (Feb. 22 issue)¹ as suggestive of intraaortic endocarditis does not even warrant a diagnosis of possible endocarditis, according to the Duke criteria.² At admission, the patient had ...

To the Editor: A healthy 29-year-old medical resident awoke one Sunday morning with intense pain in the right shoulder. He did not recall any recent injuries or trauma and had not participated in any sports or physical exercise recently. He consulted a ...