To the Editor: The report by Wheeler et al. (Sept. 1 issue)¹on an outbreak of hepatitis A arouses concern because of the number of people infected from a single contaminated food and because of the severity of the disease, reflected in the rates of ...

To the Editor: The report by Gulati et al. (Aug. 4 issue)¹and the accompanying editorial by Kraus and Douglas² claim that the nomogram for predicting exercise capacity in women according to age and level of metabolic equivalents (MET) is unique. However, ...

To the Editor: With regard to the article by Clark et al. (Aug. 18 issue),¹ we would like to call attention to the usefulness of fine-needle aspiration biopsy for soft-tissue sarcoma. In their article, the authors point out that fine-needle aspiration ...

To the Editor: In her discussion of Case 24-2005 (Aug. 11 issue),¹ Dr. Ryan recommended adjuvant therapy with anastrozole (Arimidex) for a postmenopausal woman with hormone-receptor–positive breast cancer. Although the Arimidex, Tamoxifen Alone or in ...

To the Editor: Linezolid belongs to a family of antimicrobial agents (oxazolidinones) that inhibit bacterial protein synthesis by preventing the fusion of 30S and 50S ribosomal subunits.¹ Hyperlactatemia, metabolic acidosis, and peripheral neuropathy are ...

To the Editor: The opportunity to study the effects of refeeding after prolonged fasting is rare. We recorded anthropometric, biochemical, and endocrine changes during the refeeding period after a much-publicized 44-day fast by David Blaine, a ...

Epidemic poliomyelitis first appeared in the United States a century ago, at a time when America was rapidly evolving from its postcolonial agrarian roots toward industrialization, urbanization, and the ascension of the middle class. Polio, a new “...

Comprehensive textbooks for a medical specialty are difficult to write or update in these times because of the rapid pace of discoveries and of the evolution of concepts and because of the large number of review articles in international journals that ...

Bone metastasis is an important clinical problem affecting approximately 350,000 people in the United States. After tumors have metastasized to bone, the cancer becomes incurable. In clinical trials in the past, bone metastases were not considered ...

Abatacept for Rheumatoid Arthritis Refractory to Tumor Necrosis Factor α Inhibition Original Article, N Engl J Med 2005:353;1114-1123.. On page 1121, in Figure 3B, the key was incorrectly labeled. The light blue bars represent abatacept, and the dark blue ...

Severe Sepsis and Therapy with Activated Protein C Editorial, N Engl J Med 2005:353;1398-1400.. On page 1398, in the right-hand column, the P value in line 15 of the first full paragraph should have read “P=0.06,” rather than “P=0.006,” as printed.