To the Editor: In the study reported by Sauer et al. (Oct. 21 issue),¹ 18 percent of the patients in the postoperative-chemoradiotherapy group were found to have stage I disease, and about 10 percent were found intraoperatively to have distant metastases ...

To the Editor: Bennett et al. (Sept. 30 issue)¹ calculated the “incidence” of pure red-cell aplasia among patients receiving epoetin therapy by reviewing reports from the Adverse Event Reporting System of the Food and Drug Administration (FDA). The ...

To the Editor: In a study of adults with bacterial meningitis, van de Beek et al. (Oct. 28 issue)¹ noted the following: 14 percent were comatose on admission, those with opening pressures above 400 mm of water were more likely to be admitted in a coma (...

To the Editor: In his Perspective article, Dr. Garber (Oct. 14 issue)¹ appropriately alerts us to the potential for conflicts of interest when an academic medical center forms a relationship with a business company. New York–Presbyterian Hospital is very ...

To the Editor: Kratz et al. report in the October 7 issue¹ the revised laboratory reference values for tests commonly ordered at the Massachusetts General Hospital. We noticed that the normative range for 25-hydroxyvitamin D is below what is now the ...

To the Editor: In their Clinical Problem-Solving article “Footprints” (Sept. 30 issue),¹ Kassutto and Daily present the case of a patient with erythema nodosum, bilateral hilar lymphadenopathy, and a positive purified-protein-derivative (PPD) test. The ...

To the Editor: The diagnosis of resistance to thyroid hormone requires careful analysis of clinical and laboratory data. The presence of Hashimoto's thyroiditis in a patient with resistance to thyroid hormone makes hypothyroidism and its treatment more ...

To the Editor: Rifampin is often used to treat tuberculosis.¹ Isley² reported on a patient with treated hypothyroidism (euthyroid while taking stable doses of thyroxine) but who again became hypothyroid after receiving rifampin. We now report on three ...

“I abhor the traffic in testimony to which I regret to say men of science sometimes permit themselves to condescend,” Attorney General Sir Alexander Cockburn famously observed after considering the conflicting medical testimony given at Dr. William Palmer'...

Some specialty areas of medicine are again facing the problem of obtaining affordable liability insurance for medical negligence. Most medical providers and liability insurers blame the problem on plaintiffs' lawyers and wayward juries, whereas consumer ...

Myths often serve a protective role by providing comfort so that deeply held convictions are not challenged. With respect to medicine in the Third Reich, two such myths are the beliefs that only marginal physicians in extreme situations participated in ...

Is it possible to increase human longevity dramatically? And if so, at what price? By prolonging an old age of chronic disease and disability, mental incompetence, functional decline, and dependency, perhaps even sacrificing, in a devil's bargain, what it ...

Genotypes and Phenotypes — Another Lesson from the Hemoglobinopathies Perspective, N Engl J Med 2004:351;1490-1492.. On page 1492, lines 2 and 3 of the second full paragraph should have read, “coding for phenylalanine instead of leucine,” rather than “...

New Drugs for Rheumatoid Arthritis Correspondence, N Engl J Med 2004:351;2659-2661.. On page 2659, the first footnote in Table 1 should have read, “The inclusion criteria required patients to have active rheumatoid arthritis,” rather than “to have ...