To the Editor: In the important study by Walsh et al. (Sept. 30 issue),¹ the most unexpected finding was the difference in response rates between the liposomal amphotericin B group and the caspofungin group among patients who had aspergillosis at ...

To the Editor: Solomon et al. (Nov. 4 issue)¹ suggest that the ocular chlamydia that causes trachoma can be eliminated by a single mass antibiotic treatment. Two years after distributing oral azithromycin in a village, they identified only a single ...

To the Editor: In their recent articles on rising health care costs, economists Paul Ginsburg (Oct. 14 issue)¹ and Joseph Newhouse (Oct. 21 issue)² and presidential candidates John Kerry and George Bush (Oct. 28 issue)³ do not directly address the well-...

To the Editor: In his Clinical Practice article on Bell's palsy, Gilden (Sept. 23 issue)¹ recommends treatment of the patient in the vignette with oral prednisone. The Cochrane Collaboration² has pointed out that the statement of the American Academy of ...

To the Editor: In their review of pulmonary hypertension, Farber and Loscalzo (Oct. 14 issue)¹ suggest that chronic hypoxia causes pulmonary hypertension by producing structural changes in the vasculature. This widely accepted view postulates two major ...

To the Editor: In reference to the discussion of pernicious anemia in Case 30-2004 (Sept. 23 issue),¹ the practice in the United Kingdom for many years has been a regimen of four intramuscular injections of 1000 μg of hydroxocobalamin (an injectable form ...

To the Editor: West Nile virus is a flavivirus that has caused seasonal outbreaks of disease in humans since its introduction into the United States in 1999. The clinical presentation is highly variable, ranging from asymptomatic disease to mild ...

In the absence of well-reasoned skepticism, medical practice can become enraptured with the potential of new technological advances. In this insightful how-to book on health care, Welch provides a comprehensive overview of current challenges in cancer ...

In this excellent and timely book, George Prendergast has created a primer for academically trained laboratory scientists about the challenges of developing modern drugs. The growing expectation among the public that scientific advances in cancer research ...

Several outstanding books describe the science and clinical practice of hematopoietic stem-cell transplantation (HSCT), but information in these works generally is based on data collected from studies in adult patients. HSCT plays an important role in the ...

Modern therapy for childhood cancer is a double-edged sword. With judicious combinations of chemotherapy, radiotherapy, and surgery, as well as supportive care, physicians can design treatment protocols that will secure long-term disease-free survival in ...