To the Editor: Srinivasan and colleagues (March 17 issue)¹ report the transmission of rabies virus from an organ donor to four recipients. Three recipients had neurologic deterioration and encephalitis and died about five weeks after transplantation; one ...

To the Editor: Arad et al. (Jan. 27 issue)¹ report that LAMP2 mutations (Danon's disease) are an important cause of hypertrophic cardiomyopathy. That one of their patients had an “adolescent response to cardiac disease,” however, strangely misses the ...

To the Editor: Okie's Perspective article (March 17 issue)¹ on the Food and Drug Administration (FDA) covers important ground but misses a key issue. No drug is absolutely safe; drug safety is always assessed in relation to the disease being treated. We ...

To the Editor: Preston's editorial (March 17 issue)¹ on obesity and its influence on longevity, which accompanies the report by Olshansky et al.,² focused my thinking on morbidity versus mortality. Preston wrote that “the current life expectancy at birth ...

To the Editor: Dual infection with different strains of HIV type 1 (HIV-1) is reported with increasing frequency, attributed mostly to coinfection at the time of the primary infection. However, some patients were superinfected with a second virus after ...

In the relatively brief time since September 11, 2001, legions of articles have been published, grants submitted, journals launched, and textbooks edited on the subject of terrorism involving biologic agents. Much of the work has focused on the agents ...

Hardly a week passes without a new report describing an association between vascular risk factors and dementia. With our rapidly growing elderly population, dementia is becoming an increasing public health burden. This book is an update on the link ...

The recognition that modest changes in temperature may modulate the outcome after global or focal cerebral ischemia, or both, has led to the use of mild-to-moderate hypothermia to reduce reperfusion injury in diverse clinical settings — for example, after ...

This book is an excellent guide for any physician who transfuses blood, because it applies clinically relevant information to the decision to transfuse blood components. The book provides guidance for the clinical practice of blood-component therapy, and ...

What Ails the FDA? Perspective, N Engl J Med 2005:352;1063-1066.. On page 1064, in the last paragraph in the left-hand column, line 3 should have read, “For new molecular entities (drugs whose active ingredient has never before been approved in the United ...

Therapy for Colorectal Cancer Correspondence, N Engl J Med 2005:352;1820-1822.. In the letter by Kountouras et al., lines 3 through 7 should have read, “Regional infusion of interleukin-2 or interferon gamma through the hepatic artery, combined with ...