To the Editor: The statement from the International Committee of Medical Journal Editors (ICMJE) with respect to the registration of clinical trials (Sept. 16 issue)¹ advocates the use of www.clinicaltrials.gov as a registry. I am astonished by this ...

To the Editor: Go et al. (Sept. 23 issue)¹ estimated the glomerular filtration rate (GFR) with the simplified four-variable Modification of Diet in Renal Disease (MDRD) formula. Almost half the subjects in their study population (41.7 percent) did not ...

To the Editor: Petrylak et al. (Oct. 7 issue)¹ conclude that combination treatment with docetaxel and estramustine should be used as initial therapy for androgen-independent metastatic prostate cancer. Several key points that are necessary to reach this ...

To the Editor: Two articles in the September 23 issue, by Bloche¹ and Mariner,² give the impression that the issue of managed-care liability is settled — that the Supreme Court has “made up its mind” to immunize managed-care organizations (MCOs) from ...

To the Editor: Piccirillo (Aug. 26 issue)¹ recommends that acute bacterial sinusitis be treated with 500 mg of amoxicillin three times daily. Pneumococcus is an important cause of this condition and, at present, 40 percent of pneumococci in the United ...

To the Editor: Hotez et al. (Aug. 19 issue)¹ suggest waiting for socioeconomic reforms to eliminate hookworm infection, a condition that afflicts 740 million persons. However, chronic anemia is an enormous handicap and limits the prospects of a better ...

To the Editor: In her otherwise excellent review of thiazolidinediones, Dr. Yki-Järvinen (Sept. 9 issue)¹ states that “the effects of rosiglitazone or pioglitazone on the size of LDL [low-density lipoprotein] particles have not been studied in a double-...

To the Editor: We wish to report initial success in treating a boy with surfactant protein C deficiency. The patient was first admitted to the hospital at five months of age with severe respiratory distress that followed a viral respiratory infection. ...

Because the structural role of the skeletal system is obvious, and because the hardness of mineralized bone matrix and the prolonged duration of adult bone mass emphasize its solidity, the dynamic and multifunctional nature of the skeleton are not an ...

Cambridge, England, where the authors of Soft Tissue Rheumatology are from, is known for its scientifically rigorous approach to medicine, and this book is very effective at capturing the current knowledge in the field of soft-tissue rheumatology. The ...

Male reproductive health has become an important focus of health services in many countries. Poor semen quality is a widespread problem, and both young and elderly men often seek medical advice regarding symptoms of hypogonadism, including sexual ...

This book — whose authors include 10 Chicago urologists, 12 other U.S. urologists, and an eminent urologist from Ireland — reviews the anatomy, pathophysiology, and causes of benign prostatic hypertrophy, or hyperplasia (BPH), and discusses the assessment ...