To the Editor: In their study of homocysteine as a predictive factor for hip fracture in older persons, McLean et al. (May 13 issue)¹ do not thoroughly discuss the role of physical activity, which may influence the association between homocysteine levels ...

To the Editor: Schuelke et al. (June 24 issue)¹ describe a child with muscle hypertrophy in association with a mutation in the myostatin gene. Another possible case of a myostatin mutation in an exceptionally strong child was described more than 2500 ...

To the Editor: Dr. Steinbrook (June 3 issue)¹ joins the American College of Obstetricians and Gynecologists in urging “all obstetrician-gynecologists to provide advance prescriptions for emergency contraception to all women of reproductive age at every ...

To the Editor: In their review of autoimmune polyendocrine syndromes, Eisenbarth and Gottlieb (May 13 issue)¹ do not, in our view, sufficiently discuss autoimmune hypoparathyroidism and recent advances in its understanding. Autoimmune hypoparathyroidism ...

To the Editor: Case 18-2004, discussed by Shellito et al. (June 10 issue),¹ concerns the management of rectal cancer and contains the recommendation that adequate pathological examination of resection specimens requires retrieval of no fewer than 15 ...

To the Editor: Langerhans'-cell histiocytosis (LCH) is a rare disorder characterized by tissue infiltrates of CD1a+ Langerhans' cells, eosinophils, neutrophils, macrophages, and lymphocytes. Systemic treatments for refractory LCH are unsatisfactory and ...

Toward the end of the 18th century, Immanuel Kant argued that psychology could never be a science, because the mind, being immaterial, could not be measured. But less than 100 years later, Wilhelm Wundt established the first psychological laboratory to ...

Writing one's life is a risky venture of memory, invention, and desire. With intellectual depth and formal rigor, Roy Vagelos and the historian Louis Galambos have written a serious and nourishing report of Vagelos's life in medicine, science, and the ...

High-Bone-Mass Disease and LRP5 Correspondence, N Engl J Med 2004:350;2096-2099.. In the letter by Whyte et al., on page 2097, in the right-hand column, line 8 of the first full paragraph should have read “L1 to L4,” rather than “L1 to L7,” as printed. We ...

Hypertrophic Obstructive Cardiomyopathy Clinical Practice, N Engl J Med 2004:350;1320-1327.. As a clarification to the information provided on page 1323 in Table 2 regarding the recommended doses of beta-blockers, the authors have submitted the following ...