To the Editor: In their article about excision margins for melanoma, Thomas et al. (Feb. 19 issue)¹ conclude that a 3-cm margin of excision, as compared with a 1-cm margin, is associated with reduced locoregional recurrences. But is a reduction in ...

To the Editor: Shane et al. (Feb. 19 issue)¹ found minimal differences between the benefits conferred by alendronate and those conferred by calcitriol, and the authors speculated (as did Lindsay, in an accompanying Perspective article²) that combination ...

To the Editor: Celli and colleagues (March 4 issue)¹ propose the use of a new index (the BODE index) that has excellent predictive power with regard to outcome in chronic obstructive pulmonary disease (COPD). The BODE index combines four variables: the ...

To the Editor: In their article on pericardial constriction, Sagristà-Sauleda et al. (Jan. 29 issue)¹ note the critical contribution of the visceral layer of the pericardium to the pathogenesis of constrictive pericarditis. We fully agree with this point ...

To the Editor: The medical mystery in the April 1 issue¹ involved a 23-year-old Peace Corps volunteer in Gambia. Painless ulcers developed on his lower legs (Figure 1A) and did not respond to local or systemic antimicrobial therapy.

A slit-skin smear ...

To the Editor: Sheridan et al. (Feb. 19 issue)¹ fail to consider that carbonaceous sputum, confusion, agitation, dyspnea, and lactic acidosis in their burned patient are all signs of potential cyanide poisoning from smoke inhalation. This oversight is ...

To the Editor: Twenty-four-hour ambulatory blood-pressure monitoring is used to differentiate so-called white-coat hypertension from more prolonged and frequent hypertension.¹,² We describe a patient in whom the monitoring device itself was instrumental ...