To the Editor: According to the report by Freedman et al. (Feb. 5 issue),¹ the median ratio of arachidonic acid to docosahexaenoic acid in patients with cystic fibrosis was higher than that in healthy subjects. Because linoleic acid is metabolized to ...

To the Editor: Meunier et al. (Jan. 29 issue)¹ studied the effects of strontium ranelate on the risk of vertebral fracture in women with postmenopausal osteoporosis in a placebo-controlled trial. We are surprised by their statement, “To date, no ...

To the Editor: Levine et al. (Feb. 12 issue)¹ have shown that increased levels of soluble fms-like tyrosine 1 (sFlt-1) and reduced levels of placental growth factor (PlGF) predict the development of preeclampsia, a few weeks before the onset of clinical ...

To the Editor: Rhoden and Morgentaler¹ and Snyder² (Jan. 29 issue) assuage the anxiety of physicians who administer testosterone to older men because the men report andropause, a collection of ill-defined maladies related to male aging. Their position in ...

To the Editor: We would like to add some information to Young and Brown's review (Feb. 5 issue)¹ of parvovirus B19 infection and myocarditis. We studied myocardial tissue from five patients with fulminant parvovirus B19–associated myocarditis by in situ ...

To the Editor: In their review of lung-cancer management (Jan. 22 issue),¹ Spira and Ettinger fail to mention the value of endoscopic ultrasonography with fine-needle aspiration in the staging of non–small-cell lung cancer. This method can identify lymph ...

To the Editor: Neuroblastoma is the most common form of malignant solid tumor during childhood. Japan is the only country in which mass screening for neuroblastoma has been adopted as a national policy, and the program has been conducted since 1984. In ...

Jonathan Weiner is a talented science writer. He won a Pulitzer Prize for his book on Darwin's finches and a National Book Critics Circle Award for one on the genetics of behavior in drosophila. Here he tells the poignant story of Stephen Heywood, a ...

The brief personal introduction that ends with “. . . and I'm an alcoholic” is often parodied in film and print, but it captures the central discovery that Bill Wilson stumbled on as he found the path to freedom from his own addiction to alcohol. It was ...

Frederick Holmes, physician and professor emeritus of medicine at the University of Kansas Medical Center, took a sabbatical leave in 1991 to study British history and became enamored with the Stuart family of 17th-century kings and queens (Figure). The ...