To the Editor: In their meticulous study of type 1 diabetes (June 5 issue), Perkins et al.¹ overlook dietary protein intake as a potentially important determinant of fluctuations in urinary albumin excretion over time. Dietary protein intake has been ...

To the Editor: Priori et al. (May 8 issue)¹ describe a new risk-stratification algorithm for the long-QT syndrome, one based on genotype. As the authors note, the natural history of the long-QT syndrome varies not only among families with mutations that ...

To the Editor: Campagna et al. (May 22 issue)¹ provide a comprehensive review of the mechanisms of actions of inhaled anesthetics. I was surprised, however, by some of the information they provide in Table 2 of their article. First, the authors suggest ...

To the Editor: In Figure 1 of their article, Wooster and Weber (June 5 issue)¹ ignore an important paradox by dismissing mutations in the ATM (ataxia–telangiectasia mutated) gene as not contributing to breast cancer. Current theories propose that ATM ...

To the Editor: The new editor of the Case Records of the Massachusetts General Hospital, Nancy Lee Harris, rightly notes in her editorial (May 29 issue)¹ that at the turn of the 21st century, there is much less need than in previous decades for exercises ...

To the Editor: Mello et al. (June 5 issue)¹ do an excellent job of summarizing the current medical malpractice crisis but overlook one of the simplest solutions. Physicians, unlike those in virtually any other business or industry, are unable to pass on ...

To the Editor: Although secondary cancer is a well-established long-term complication of hematopoietic stem-cell transplantation,¹ the transmission of hematologic cancers through marrow or solid-organ transplantation is exceptional.² Moreover, to our ...

Why should this book about the commercialization of higher education, written by a former president of Harvard University, be reviewed in a medical journal? And what relevance does his thoughtful analysis of the corrosive effects of big-time athletics and ...

Global approaches to health began to be conceived as rich nations embarked on the exploration and colonization of poor nations in the tropics. For much of the first half of the 20th century, these approaches were focused on gaining an understanding of the ...

Insurance inherently involves collective destinies among members of a community — a sharing of the risk of loss from untoward events. The fourth report from the Institute of Medicine's Committee on the Consequences of Uninsurance, A Shared Destiny: ...

Health care costs are out of control, the quality of health care is frightfully low, and far too many people are uninsured. The solution, according to George Halvorson and George Isham, is managed care. This is not your father's managed care. It is the ...