To the Editor: Hylek and colleagues (Sept. 11 issue)¹ report that in patients with nonvalvular atrial fibrillation who were admitted with stroke, an international normalized ratio (INR) of less than 2.0 was associated with a greater severity of stroke ...

To the Editor: Askie et al. (Sept. 4 issue)¹ report the effects of oxygen-saturation targeting at 32 weeks of postmenstrual age on outcomes in premature infants. First, why did the authors define “standard saturation” as 91 to 94 percent and “high ...

To the Editor: Lu et al. (Sept. 18 issue)¹ report human immunodeficiency virus (HIV) infection presenting as monoclonal gammopathy of undetermined significance (MGUS) in a 46-year-old man and argue that young patients with MGUS should be screened for HIV ...

To the Editor: In Dr. Mehler's discussion of the physiological complications of bulimia nervosa (Aug. 28 issue),¹ he emphasizes the diagnostic usefulness of urinary electrolyte measurements and concludes that low urinary potassium and sodium ...

To the Editor: In their excellent review of the molecular epidemiology of tuberculosis, Barnes and Cave (Sept. 18 issue)¹ recommend that the Centers for Disease Control and Prevention (CDC) support newer, more rapid genotyping tests. In fact, the CDC is ...

To the Editor: Camí and Farré (Sept. 4 issue)¹ provide a comprehensive review of the neuronal and behavioral mechanisms involved in drug addiction. Their information on the potential for abuse of cannabinoids, however, is outdated. The authors claim that,...

To the Editor: The insights provided by Korner and Leibel (Sept. 4 issue)¹ into the interplay between the digestive and nervous systems are cogent, but the figure in their article seems to contain an error or, at least, an oversimplification. A neuron ...

To the Editor: The detection of aspergillus galactomannan antigenemia is a method used in the diagnosis of invasive aspergillosis.¹,² Some transient false positive reactions have been reported with the use of enzyme-linked immunosorbent assays in ...

To the Editor: We report the case of a 34-year-old man who presented with a two-month history of painful keratotic plaques that involved the skin surrounding the ears, the nose, and the soles in association with polyarthritis. He had had a diarrheal ...

The only thing missing from this book is a question mark in the title. Better Than Prozac is about the long road that neuropsychopharmacology has traveled and about hopes for its future, particularly with respect to creating better drugs. Drugs that treat ...

Prozac on the Couch is a creative, intelligent, and provocative challenge to the notion that biologic psychiatry has replaced psychoanalysis as the dominant therapeutic model in psychiatry. Tracing treatments for depression, anxiety, and other mental ...

Schizophrenia is a worldwide public health problem that carries substantial personal and social burdens. As the fourth leading cause of disability among adults, schizophrenia compromises the social and occupational functions of those who have this ...

Historically, epidemiologic contributions to research on schizophrenia have involved descriptive studies of the incidence and prevalence of the disease and associated risk factors, as well as longitudinal studies of its course and outcome. The ...