To the Editor: More than 20 years have elapsed since Wohl and Chernick speculated about the possible clinical efficacy of inhaled epinephrine in the treatment of infants with acute bronchiolitis.¹ It turns out, according to the study reported by ...

To the Editor: Lee and colleagues (July 10 issue)¹ provide strong and pertinent data indicating the benefit of prolonged treatment with low-molecular-weight heparin for the prevention of recurrent venous thromboembolism in patients with cancer. ...

To the Editor: In their review of valvular heart disease in pregnancy, Reimold and Rutherford (July 3 issue)¹ do not address the early puerperium. In our opinion, this period may be crucial. Many clinicians tend to believe that pregnancy in a patient at ...

To the Editor: I believe that Table 2 of the article by Nabel (July 3 issue)¹ gives misleading information concerning apparent mineralocorticoid excess: this disease is said to be due to mutations in the gene encoding 11β-hydroxylase, but in fact, ...

To the Editor: Calabrese et al. (June 5 issue)¹ describe cardiac transplantation in a patient with a 15-year history of human immunodeficiency virus type 1 (HIV-1) infection and multiple opportunistic infections who had dilated cardiomyopathy due to ...

To the Editor: The “compound” umbilical-cord knot reported by Camann and Marquardt (July 10 issue)¹ is topologically two distinct knots that were probably “tied” at separate times. First, an overhand knot probably formed as the fetus passed through a ...

To the Editor: The limitations of the three licensed typhoid vaccines that precluded their use in children younger than five years old have been overcome by a Vi conjugate vaccine (Vi-rEPA, a conjugate of the capsular polysaccharide of Salmonella typhi, ...

Modern scholarship about the relation between law and medicine is replete with impressive research and brilliant analyses, but wisdom, reflecting experience and compassion, is less common. In Refusing Care: Forced Treatment and the Rights of the Mentally ...

During the past two decades, the diagnosis of Alzheimer's disease and the characterization of patients with this disease have progressed to the point where we now feel capable of identifying and describing the presymptomatic stage of the disease and ...

Demographic changes in industrialized countries grow more compelling with each census. In many of these countries, 15 percent of the population or more is older than 65 years of age. In the United States, people in this age group make up 13 percent of the ...