To the Editor: The interesting study by Small et al. (Oct. 10 issue)¹ showed that two potentially synergistic adrenergic-receptor polymorphisms are associated with a risk of congestive heart failure. Since this may indeed give rise to genotype-targeted ...

To the Editor: The findings of Tuomala et al. (June 13 issue)¹ contradict earlier results from Europe² showing that exposure to highly active antiretroviral therapy increases the risk of premature delivery by a factor of nearly three. The cumulative ...

To the Editor: In his Clinical Practice article (Aug. 15 issue),¹ Dr. Flemons discusses several risks associated with obstructive sleep apnea. Recent reports have revealed a number of “unexplained” postoperative cardiopulmonary arrests in surgical ...

To the Editor: We disagree with the statement made by Brent and Birmaher (Aug. 29 issue)¹ that overdoses of selective serotonin-reuptake inhibitors (SSRIs) are rarely toxic. Although overdoses of an SSRI (as the single ingested agent) are rarely fatal,²,^...

To the Editor: A large variety of infectious agents are associated with fever, headache, and ocular inflammation, as discussed by Mushlin et al. in Case 33-2002 (Oct. 24 issue).¹ Whenever lymphadenopathy is involved, cat scratch disease due to Bartonella ...

To the Editor: I am a retired biostatistician with recent service on an institutional review board (IRB), and my experience supports the observations of Schulman et al. (Oct. 24 issue)¹ and suggests that the implications of their findings are serious and ...

The rising tide of asthma in the Western world invites many questions. Why is the incidence of asthma increasing? Does avoidance of allergens help? When should treatment be started, and what are the therapeutic options? Anyone faced with these and related ...

This book aims to fill a niche. It is meant not for critical care specialists but rather for clinicians with intermittent responsibilities in the care of critically ill patients: internists and hospitalists, as well as trainees and students. But the book ...

Chronic obstructive lung disease, or chronic obstructive pulmonary disease (COPD), is characterized by progressive limitation of airflow due to inflammation of small airways and fibrosis and destruction of lung parenchyma (emphysema). The principal cause ...

Occupational disorders are common, but clinicians who can recognize and manage them are not. Recent headlines reminded us of this gap in medical education, as we struggled to cope with outbreaks of anthrax in postal workers and cough in firefighters at ...