To the Editor: Heeschen et al. (March 20 issue)¹ show that troponin T and soluble CD40 ligand independently predict the outcome in patients with acute coronary syndromes and that the increased risk conferred by elevated CD40 ligand levels is reduced by ...

To the Editor: Martin et al. (March 20 issue)¹ and, in her Perspective article, Zuger² correctly observe that the “wired” Dartmouth campus provided effective electronic means of collecting data that might have helped contain the outbreak of ...

To the Editor: In his Perspective article “A Death at Duke” (March 20 issue),¹ Dr. Campion observes, “Systems do not become safer when those involved are told, `Be more careful' or `try harder.'” As an attorney who has spent 25 years representing ...

To the Editor: Taupenot et al. (March 20 issue)¹ state in their review article that the prognostic value of chromogranin A immunoreactivity in colorectal cancer has not been established. In fact, four out of five studies identify extensive neuroendocrine ...

To the Editor: Vincent's thoughtful discussion of adverse events and our response to them (March 13 issue)¹ should be mandatory reading for all residents, attending physicians, and dentists. He correctly suggests that the academic health care culture ...

To the Editor: The article on race and genomics by Cooper et al. (March 20 issue)¹ claims that multilocus interactions are “both mathematically and biologically implausible” as risk factors for complex disease. This statement stands in strong opposition ...

To the Editor: It seems unjustified to refer to a radiographic study using barium sulfate suspension as “A Deadly Examination,” as Fruchter and Dragu do (March 13 issue).¹ The patient in this case may have died because of the aspiration of gastric ...

To the Editor: Studies of hereditary inflammatory disorders have identified novel genes and pathways that may be involved in inflammation and apoptosis generally. Mutations in one such gene, variously named NALP3, CIAS1, and PYPAF1, were recently ...

Is failure of parity conservation in physics the reason conservatives are called right-wingers and liberals are called left-wingers? If the very concept eludes you, you need to read Chris McManus's grand unified theory of asymmetry. Professor of ...

Deborah Hayden's Pox: Genius, Madness, and the Mysteries of Syphilis is the biography of an infection that has fascinated and frustrated clinicians for more than half a millennium. The book is a repository of all that had been forgotten about a sinister ...

Historical research at its best is a treasure hunt for the past, illuminated in lost documents that turn up in unexpected ways and in surprising places. Jonathan Andrews and Andrew Scull were alerted to the case book of John Monro, an 18th-century “Mad-...

Alcohol has always had a special role in the United States. From 1620, when the Puritans were forced to land on Plymouth Rock because the Mayflower had almost run out of beer, until 1933, when Prohibition was repealed in an unprecedented move, the use of ...

Alzheimer's Disease and Parkinson's Disease Review Article, N Engl J Med 2003:348;1356-1364.. On page 1358, in Figure 2, the boxed “I” in the top left corner should be an “L.”

Molecular Diagnosis of the Hematologic Cancers Review Article, N Engl J Med 2003:348;1777-1785.. On page 1780, the sentence beginning on line 4 of the left-hand column should have read “The quartile of patients with the lowest level of proliferation-...