To the Editor: In their report on the use of celecoxib as compared with diclofenac plus omeprazole to reduce the risk of recurrent ulcer bleeding in patients with arthritis, Chan et al. (Dec. 26 issue)¹ state that the probability of recurrent bleeding ...

To the Editor: The strong suggestion that aspirin has a chemopreventive effect was recently corroborated by Baron et al.¹ and Sandler et al.² (March 6 issue). Although the importance of the clinical outcome is clear, the molecular mechanism leading to ...

To the Editor: I am concerned about the justification for the inclusion of a placebo group in the study by Marcellin et al. (Feb. 27 issue).¹ No statement regarding the efficacy of interferon alfa was provided, although its side effects were highlighted. ...

To the Editor: Lee and Atwood (March 6 issue)¹ provide an example of a calcified left ventricular aneurysm visualized by computed tomography (CT). On closer inspection, the pattern of calcifications in the apical region of the left ventricle gives reason ...

To the Editor: With regard to the discussion by Friedmann et al. (March 20 issue)¹ of a mediastinal germ-cell tumor in an 18-year-old man, a malignant mediastinal germ-cell tumor in a young man should raise the suspicion of Klinefelter's syndrome (47,XXY)...

To the Editor: In his article about the right to health and the nevirapine case in South Africa, Annas (Feb. 20 issue)¹ ignores the reason why governments are reasonably and prudently reluctant to establish a right to health. In the two cases described, ...

To the Editor: The only treatment approved by the Food and Drug Administration for acute acetaminophen poisoning is a 72-hour protocol of oral N-acetylcysteine administration. Clinical experience suggests that this protocol may be excessive for many ...

To the Editor: A trial of vaccination against Lyme disease provided an opportunity for us to determine the relative frequencies of the presenting manifestations of Lyme disease and the outcomes of treatment in a large population.¹ Our goal was to ...

These days, practicing medicine in the United States is a mixed blessing. On the one hand, physicians still reap intangible rewards, including exhilaration from helping people, the privilege of sharing patients' joys and sorrows, and intellectual ...

Rohde and Wyon have put together a very useful book on community-based health care. It originated in the Symposium on Community-Based Health Care: Lessons from Bangladesh to Boston, held at the Harvard School of Public Health in November 2000. The ...

Technological Change in Health Care: A Global Analysis of Heart Attack analyzes the relation between outcomes and technological change in the treatment of acute myocardial infarction by comparing events that took place over the course of 20 years in 15 ...

This book addresses two questions. Why are there so many foreign scientists in training and research positions at the National Institutes of Health (NIH)? What is their effect on postdoctoral fellows, academic institutions, industry, and labor policies in ...