To the Editor: I am alarmed by the high rate of vaccinia-vaccine–associated morbidity (>30 percent) in the study by Frey et al. (April 25 issue).¹ In their study, there were three deviations from prior standard procedures for vaccinia vaccination²–⁵ that ...

To the Editor: In Table 1 of their article, Breman and Henderson (April 25 issue)¹ list secondary syphilis as a maculopapular eruption, noting that it has frequently been confused with smallpox. In general, it is more difficult to differentiate ...

To the Editor: Bicknell's Sounding Board article (April 25 issue)¹ includes some factual errors. Smallpox is not transmitted during its preeruptive period. It spreads only from overtly ill persons.²,³ Ring vaccination is not just for small outbreaks. It ...

To the Editor: Boylston (April 25 issue)¹ reminds us that clinical trials have been around a long time and that they are available to all, and he cites William Watson's contribution to the understanding of smallpox in 1767 as perhaps the first. But I ...

To the Editor: Radiation treatment undoubtedly reduces the risk of recurrence of in-stent restenosis. However, the findings of Waksman et al. (April 18 issue)¹ should be taken in the context of two facts. First, although the greatest need for target-...

To the Editor: The attempt of Birkmeyer et al. (April 11 issue)¹ to correlate low procedure-specific hospital volume with increased mortality has methodologic and interpretive problems. The investigators used data from the Medicare Provider Analysis and ...

To the Editor: The Image in Clinical Medicine entitled “Bronchial Cast” (March 28 issue)¹ describes a patient who had had respiratory symptoms for six months and who expectorated a bronchial cast. However, the authors do not mention the outcome. Was the ...

To the Editor: We disagree strongly with the conclusions of Cothren et al. (April 4 issue)¹ about the benefits of the polymerized hemoglobin-based oxygen carrier PolyHeme in critically ill patients with anemia who refuse transfusions. Hemoglobin-based ...

To the Editor: Babesia divergens is the primary cause of human babesiosis in Europe, resulting in fatality rates of 42 percent among persons who have undergone splenectomy and 5 percent among persons with intact spleens.¹ The known vector tick, Ixodes ...

Despite its title, this book is not the story of a deliberate hunt for a killer virus. It is the story of the almost accidental opening of new vistas in virology that led to a Nobel prize. It is the story of the boy from Brooklyn who became the persistent,...

This is a comprehensive, informative, and well-referenced monograph on the main proteins involved in iron metabolism, including transferrin, ferritin, lactoferrin, and the iron-transport proteins and on the relevant aspects of iron absorption and cellular ...

This book covers many of the topics in vascular medicine that currently are prominent in the scientific, clinical, and lay press. Part I deals with mechanisms of hypercoagulability; the roles of cells, cytokines, and inflammation in the pathogenesis of ...