To the Editor: Imperiale et al. (June 6 issue)¹ presented a well-designed and important study on the effectiveness of screening for colon cancer in persons 40 to 49 years of age. However, the conclusions appear perhaps to be driven more by cost than by ...

To the Editor: We concur with Lachmann et al. (June 6 issue)¹ that therapeutic advances demand accurate typing of amyloid deposits.² Our experience with 465 patients with sporadic, biopsy-proven, systemic amyloidosis indicates that immunoelectron-...

To the Editor: Perl et al. (June 13 issue)¹ report that prophylaxis with mupirocin did not reduce the overall rate of Staphylococcus aureus infections at surgical sites but did significantly reduce the rate of nosocomial S. aureus infections. Although ...

To the Editor: In her review of the management of human immunodeficiency virus (HIV) infection during pregnancy (June 13 issue),¹ Watts recommends addressing coexisting herpes simplex virus (HSV) infection as one would for a nonpregnant patient. However, ...

To the Editor: Fuchs (June 6 issue)¹ correctly points out that new insurance plans that decrease sharing of risk within companies will erode the social-insurance qualities of employment-based health insurance. This argument leads to the impression that ...

To the Editor: Hallett and colleagues (June 6 issue)¹ describe kissing-triggered reactions to food allergens. We would like to point out that kissing may lead to allergic reactions to far more than food. Liccardi et al.² recently reported the induction ...

To the Editor: Inhaled corticosteroids are increasingly being used for the prophylactic treatment of asthma in children. The benefits have been well documented; however, the potential risk of growth suppression has not been fully investigated. Recent ...

To the Editor: The United States leads all other countries in productivity with respect to medical research.¹–³ However, the relative contributions of countries to research are changing over time.

We examined different countries' shares of basic-science ...

The antibiotic era, barely 60 years old, is increasingly challenged by the continued emergence of drug-resistant organisms. The variables that currently predict the level of resistance in a community (or a hospital) are the misuse of antibiotics and the ...

Sepsis, defined in its broadest sense as the syndrome evoked by the host response to infection, remains one of the most challenging problems in intensive care medicine. According to the Centers for Disease Control and Prevention (CDC), 500,000 cases of ...

During the past two decades, travel medicine, a relatively new medical specialty, has grown in response to the enormous increase in international travel. The worldwide number of international tourist arrivals in 2001 was 693 million, which represented a ...

The contest between malaria and humans may have begun in prehominid primates, and it continues unabated to the present day, with no resolution in sight. Malaria prevails in Africa, South Asia, and the Amazon and continually threatens the developed world. ...