Issue IndexA searchable index of tables of contents
Find An Issue
Table of contents for
September 12, 2002 Vol. 347 No. 11
- Free Full Text
A total of 695 men with early prostate cancer were randomly assigned to radical prostatectomy or watchful waiting. After a median follow-up of more than six years, more deaths due to prostate cancer had occurred in the watchful-waiting group, but overall survival in the two groups was essentially the same.
In this companion to the report by Holmberg et al. on survival in a randomized comparison of radical prostatectomy with watchful waiting among men with localized prostate cancer, sexual dysfunction and urinary leakage were more common in the radical-prostatectomy group, but the subjective quality of life in the two groups was similar.
- Free Full Text
Although microalbuminuria presages diabetic nephropathy, it may be a relatively late sign. Nocturnal hypertension may be an early indicator of diabetic nephropathy. In this study, investigators used 24-hour ambulatory blood-pressure monitoring in a prospective study of 75 subjects with type 1 diabetes mellitus who had normal blood pressure and urinary albumin excretion at enrollment. Over time, microalbuminuria developed in 14 subjects. An increase in nocturnal blood pressure preceded the development of microalbuminuria. The normal nocturnal dip in blood pressure had a negative predictive value of 91 percent for the development of microalbuminuria and was associated with a 70 percent reduction in risk.
- Free Full Text
The collapse of and fires at the World Trade Center in New York on September 11, 2001, resulted in large quantities of airborne material. The authors report on a syndrome characterized by severe cough, reductions in forced vital capacity and forced expiratory volume in one second, and bronchial hyperresponsiveness in 332 firefighters who worked at the site. In most, the cough lasted more than six weeks but resolved spontaneously or with treatment. Computed tomographic scans showed air trapping and bronchial-wall thickening.
- Free Full Text
A 30-year-old man reports a two-year history of heroin use. For the past year, he has been using intranasal heroin every day. He has undergone detoxification twice at a local opioid-abuse treatment program but began using heroin within two days after discharge each time. He has heard of methadone but fears that he will lose his business if he is recognized attending the local program. How should this patient be treated?
Respiratory protection is important in many occupations involving exposure to gases, vapors, or particles, including biologic agents. This article reviews the types of respiratory protection and the necessity for the proper selection and use of these devices. Respirators have predictable physiological effects, and under conditions of low oxygen levels, improper use of a respirator increases the risk of asphyxiation.
Hormonal emergency contraception is safe, effective, and available by prescription in the United States. This article explains why dropping the prescription requirement for emergency contraception would pose no risk to women and would improve public health by preventing unintended pregnancies. The author points out that over-the-counter sale of emergency contraceptive products is appropriate, because women are easily able to determine when and how to use them.
- Free Full Text
- Free Full Text
- Free Full Text
- Free Full Text
- Free Full Text
- Free Full Text
- Free Full Text
- Free Full Text
- Free Full Text
