Coronary arterial occlusion due to thrombosis is the cause of most cases of myocardial infarction accompanied by ST-segment elevation. Rapid restoration of blood flow to jeopardized myocardium limits necrosis and reduces mortality. This can be ...

For many years, the conventional wisdom, backed by observational epidemiologic studies, has held that “replacement” of estrogen after menopause would restore the relative protection from cardiovascular disease enjoyed by premenopausal women as compared ...

The author acknowledges that the presence of family members during resuscitation procedures is not always desirable or possible. However, she endorses programs at hospitals that would allow family members to be present according to their wishes. She notes that the attitudes of physicians and nurses are the greatest barriers to establishing such programs.

To the Editor: Rose et al. (Nov. 15 issue)¹ performed a seminal trial of the use of a left ventricular assist device for end-stage heart failure. However, to gauge the full extent of the effect of invasive therapy with a left ventricular assist device on ...

To the Editor: Rivers et al. (Nov. 8 issue)¹ report on goal-directed therapy for severe sepsis and septic shock. Although their findings are interesting and provocative, they should be interpreted with caution. The end points of therapy and the treatment ...

To the Editor: The article by Gortmaker et al. about combination therapy including protease inhibitors in children with human immunodeficiency virus type 1 (HIV-1) infection (Nov. 22 issue)¹ includes no data about the side effects of protease inhibitors. ...

To the Editor: We disagree with Feldman et al. and Hornick (Nov. 29 issue)¹,² about establishing a diagnosis of primary pneumonic tularemia on the basis of clinical symptoms and a single high titer of anti–Francisella tularensis antibody alone, even ...

To the Editor: In discussing the case of paraneoplastic ganglionopathy with encephalopathy (Dec. 13 issue),¹ Amato and Anderson focused on the differential diagnosis and the causes of sensory ganglionopathies. Because of the primary impairment of T-...

To the Editor: Frank et al. (Dec. 6 issue)¹ make the case that managed care enhances the affordability and feasibility of parity in coverage for mental health care because of controls implemented by managed-care organizations on the utilization and costs ...

To the Editor: We describe one of the two sentinel cases of West Nile encephalitis that have occurred in humans in Massachusetts. Both cases involved elderly Massachusetts residents, one of whom died from West Nile virus infection in mid-October, and ...

Readers might turn to this book seeking answers to three obvious questions about smoking among teenagers. Why do teenagers smoke? How can we prevent them from smoking? And how can we help them to quit? Unfortunately, the evidence carefully assembled and ...

Neonatology, defined by the age of the patient rather than by a system of the body, is one of the few “generalist” specialties. Although the neonatal age range of about half a year seems narrow, more development occurs between 22 weeks of gestation (the ...

Textbook of Clinical Pediatrics, edited by three Saudi Arabian pediatricians, aims at a broad audience interested in the health of children. More than 100 authors, many from Saudi Arabia, cover a wide spectrum of pediatric disorders. The book emphasizes ...