Status epilepticus is a series of successive grand mal seizures lasting minutes or even hours, without the recovery of normal consciousness. The resulting metabolic derangement of cells, depletion of the oxygen and glucose necessary for normal functioning,...

For a short time, the treatment of rectal cancer seemed clear and definitive. The 1990 National Institutes of Health consensus statement concluded, “Combined postoperative chemotherapy and radiation therapy improves local control and survival in stage II ...

Florence Nightingale raised the question in 1863, when she wrote about the number of deaths in hospitals in England.¹ Codman asked it in 1914.² Moses and Mosteller summed up the problem in a commentary on the National Halothane Study more than 30 years ...

To the Editor: Tuomilehto et al. (May 3 issue)¹ reported that counseling subjects at high risk for type 2 diabetes mellitus to reduce weight and the intake of fat and to increase physical exercise and the intake of fiber reduced the risk of diabetes by ...

To the Editor: Seligsohn and Lubetsky (April 19 issue)¹ justify not routinely testing white women for inherited thrombophilia before prescribing oral contraceptives, since “it would deny contraceptives to about 5 to 10 percent of white women . . . while ...

To the Editor: Rosenstein et al. (May 3 issue)¹ mention infectious syndromes associated with meningococcal disease. We would like to draw attention to the importance of considering meningococcal disease in patients who present with septic arthritis and ...

To the Editor: A 61-year-old man with no symptoms was found to have an enormous mass that occupied the entire right flank and pushed the right kidney down. A preoperative cytologic specimen obtained from a computed tomography–guided fine-needle biopsy ...

To the Editor: We wish to report the development of a severe coagulopathy in a patient who smoked “crack” cocaine mixed with brodifacoum, a rodenticide. The patient, a 37-year-old man, presented to an emergency room with epistaxis of several hours' ...

The Institute of Medicine's Committee on Quality of Health Care in America has issued its second and final report, Crossing the Quality Chasm: A New Health System for the 21st Century. The committee has done an excellent job, but its report is as ...

Replacement of an Avulsed Phalanx with Tissue-Engineered Bone Original Article, N Engl J Med 2001:344;1511-1514.. On page 1511, in the first paragraph of the Methods section, the values for ascorbic acid, L-glutamine, and streptomycin should have read, “...