Recently, great strides have been made in the use of various pharmacologic interventions for the treatment of patients with cardiovascular disease. One strategy, the use of lipid-altering therapy for both primary and secondary prevention, has reduced ...

Tularemia, which is caused by the gram-negative bacillus Francisella tularensis, is now a rare infection in the United States. The peak incidence was in 1939, when about 2300 cases were reported. The decline may be related to the fact that wild rabbits ...

To the Editor: In a trial comparing coronary-artery bypass surgery with stenting for the treatment of multivessel coronary disease, Serruys et al. (April 12 issue)¹ conclude that both treatments offer protection against death, stroke, and myocardial ...

To the Editor: We are surprised by the certainty with which Fiorillo et al. (Aug. 2 issue)¹ conclude that the so-called pseudomonas hot-foot syndrome accounts for the unprecedented cluster of cases they describe. All 40 cases occurred 10 to 40 hours ...

To the Editor: The case report by Srinivasan et al. (July 26 issue)¹ makes one wonder when glanders was first suspected as this patient's illness. The patient's work history included potential exposure to Burkholderia mallei without personal protective ...

To the Editor: Vochem et al. (Aug. 2 issue)¹ describe a neonate with disseminated Pseudomonas aeruginosa infection that was associated with a contaminated tub bath. Of concern is the description of ampicillin, cefotaxime, and gentamicin as “...

To the Editor: Only nine cases of acromegaly caused by pituitary carcinoma have been reported.¹ We describe a 47-year-old woman who presented in July 1996 with the features of acromegaly and an elevated mean serum growth hormone level of 58.4 mU per ...

Reductionism is, in the words of Peter Medawar, “the most successful research stratagem ever devised.” Thanks to reductive analysis, biomedical research has produced countless pieces of information. What we need from time to time is a fresh selection of ...

Medical toxicology, which encompasses the pathophysiology, diagnosis, and treatment of clinical problems related to poisoning and drug intoxication, has in the past decade become an established subspecialty with demonstrated breadth and depth of ...

Valvular Heart Disease Review Article, N Engl J Med 1997:337;32-41.. On page 38, in Table 1, the heading of the second column should have read, “End-Systolic Dimension,” not “End-Diastolic Dimension,” as printed. We regret the error.

A Comparison of Budesonide and Mesalamine for Active Crohn's Disease Original Article, N Engl J Med 1998:339;370-374.. On page 372, the sentence that begins on line 8 of the right-hand column should have read, “The median time to remission was also ...