The tragic events of September 11 have affected all our lives. In this issue of the Journal, we provide a quantitative look, in a Special Report by Schuster et al.,¹ at the initial reactions of Americans to these events. The data from the survey conducted ...

This year in the United States, 450,000 people will have a first ischemic stroke.¹–³ For these patients (including those receiving thrombolytic therapy), the primary therapeutic goals will be rehabilitation and the prevention of another stroke. The ...

Infection with the hepatitis C virus (HCV) is now the most frequent cause of chronic hepatitis, cirrhosis, and hepatocellular carcinoma in the United States and most Western nations.¹–³ Population-based surveys show that 1 to 2 percent of adults in the ...

To the Editor: At first glance, the data of Meijers-Heijboer and colleagues (July 19 issue)¹ appear to support the position that prophylactic mastectomy reduces the risk of breast cancer in carriers of a BRCA mutation. On close reading of the article, ...

To the Editor: Kreitman et al. (July 26 issue)¹ report that an anti-CD22 recombinant immunotoxin (BL22) induced complete remissions in 11 of 16 patients with hairy-cell leukemia that was resistant to cladribine. Although BL22 represents an exciting new ...

To the Editor: When discussing indications for the treatment of latent tuberculosis infection, Small and Fujiwara (July 19 issue)¹ follow the joint statement of the American Thoracic Society and the Centers for Disease Control and Prevention (CDC)² in ...

To the Editor: Arzoo et al. (July 19 issue)¹ report on a 23-year-old woman with Langerhans'-cell histiocytosis and severe pain due to osteolytic lesions, who had a good response to a 90-mg infusion of pamidronate. Although the literature on the use of ...

To the Editor: Portal hypertension is a frequent consequence of cirrhosis and may lead to dilated venous collaterals. Usually, varices due to portal hypertension develop in the lower esophagus, stomach, or rectum and rarely in other parts of the ...

To the Editor: I have a private practice, with two other family physicians, in an office in the financial district of lower Manhattan, five blocks (300 m) from the site of the World Trade Center. Most of our patients work or live in lower Manhattan, ...

The first impression this book makes is one of hugeness: it is huge in size, huge in scope, and huge in vision. This set of volumes, which weighs in at 16 kg (35 lb) and is too large to carry to one's car without advance planning, is no vade mecum. In the ...

Barrett's esophagus, a medical curiosity since its initial description in the early 1950s, has emerged as an intensively studied condition. Several factors might explain this transformation. First, Barrett's esophagus is one of the most easily studied ...

Mutation in the Gene for Bone Morphogenetic Protein Receptor II as a Cause of Primary Pulmonary Hypertension in a Large Kindred Original Article, N Engl J Med 2001:345;319-324.. On page 321, Figure 1 should have shown the 43-year-old man in generation III ...

Effects of Clopidogrel in Addition to Aspirin in Patients with Acute Coronary Syndromes without ST-Segment Elevation Original Article, N Engl J Med 2001:345;494-502.. On page 502, 20 lines from the bottom of the left-hand column, “B. Pontillo” should have ...

After the September 11 terrorist attacks, Americans experienced symptoms of psychological stress. This survey of U.S. adults performed just five days after the attacks quantifies the extent of the stress reactions.