Postoperative ileus, a temporary impairment of gastrointestinal motility, occurs universally after major abdominal surgery. This condition exacerbates nausea and vomiting, delays oral feeding, increases postoperative pain, and prolongs hospitalization. ...

In this issue of the Journal, two groups of investigators report that the treatment of a primary medical condition resulted in accelerated bone loss.¹,² In one study, by Smith et al.,¹ men with prostate cancer who were treated with leuprolide had rapid ...

At the turn of the last century, William Osler, Harvey Cushing, and other clinical leaders restructured hospital organization, established scientific research as the foundation for clinical practice, formalized clinical education, and set and enforced ...

To the Editor: Slamon et al. (March 15 issue)¹ show that the addition of trastuzumab, a monoclonal antibody against the human epidermal growth factor receptor HER2 (also known as HER2/neu), to chemotherapy in women with metastatic breast cancer that ...

To the Editor: Packer et al. (May 31 issue)¹ report that the Carvedilol Prospective Randomized Cumulative Survival Study was stopped early on the recommendation of the data and safety monitoring board because of a significant beneficial effect of ...

To the Editor: In their report of bone marrow transplantation in a case of the immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX), Baud et al. (June 7 issue)¹ incorrectly stated that our patient (described in our 1995 report²)...

To the Editor: Rituximab is a chimeric monoclonal antibody directed against the CD20 antigen expressed on most B cells and is used to treat B-cell non-Hodgkin's lymphoma.¹ Recently, rituximab has been used to treat post-transplantation ...

To the Editor: In July, a six-year-old child undergoing magnetic resonance imaging (MRI) in New York suffered a skull fracture and intracranial hemorrhage after an oxygen tank that had been brought into the room was pulled into the machine at high speed. ...

This is the third volume of a series of interviews with psychopharmacologists conducted by David Healy. Some of those interviewed are basic scientists, and some are primarily clinicians, but all have had important roles in the development of today's ...

Borderline personality disorder may be one of the most pleomorphic disorders in medicine. Patients with this diagnosis are a complex mixture of strengths and weaknesses that confuse the diagnostician and frustrate the psychotherapist. Such patients may ...

Knowledge about attention-deficit–hyperactivity disorder (ADHD) expands by the day, thanks to the efforts of many academic investigators and research centers. However, there is a plethora of books by “experts” with dubious credentials and experience. ...