Osteoporosis is a common and important cause of morbidity and mortality among postmenopausal women.¹–³ It arises as a consequence of progressive loss of bone and results in an increased risk of fracture. The destruction of trabecular microarchitecture, ...

Infants born prematurely, particularly those delivered at <32 weeks' gestation, have immature lungs and a high incidence of respiratory distress syndrome and continuing chronic lung disease, also known as bronchopulmonary dysplasia. Lung disease remains ...

Childhood acute lymphoblastic leukemia is curable in approximately 70 percent of children.¹,² Many of the children who are not cured have presenting features that are indistinguishable from those in children who are cured. We reasoned that because ...

For the clinical diagnosis of Alzheimer's disease, the criteria of the National Institute of Neurological and Communicative Disorders and Stroke (NINCDS) and the Alzheimer's Disease and Related Disorders Association (ADRDA) Work Group,¹ which include ...

Figure 1. A 68-year-old nonsmoking woman was evaluated because of progressive dyspnea and chronic lung disease. She had had middle lobe syndrome for 20 years. She had been taking 2 to 3 teaspoons (10 to 15 ml) of mineral oil at bedtime since early ...

The promise of extending health insurance coverage to all Americans appeared to have faded altogether with the demise of the Clinton health care reform effort in 1994. However, the prospects of expanding health insurance for children improved markedly ...

The organic nitrates are widely used in the management of coronary artery disease. They are given not only to patients with stable angina pectoris, but also to those with unstable angina, acute myocardial infarction, and heart failure. Although they are ...

Presentation of Case

A six-year-old boy was admitted to the hospital because of a painful hip.

The child had been well until 11 days earlier, when an upper respiratory tract infection developed. Two days later, he fell while playing and noticed mild pain ...

In this issue of the Journal, Newacheck and colleagues¹ present new evidence confirming that children from families without health insurance are far less likely to get medical care when they need it, or to get regular care from physicians in their offices,...

To the Editor: Untenable case definitions entrapped Schiødt and associates (Oct. 16 issue)¹ in their study of acetaminophen toxicity in an urban county hospital. They recognized their predicament but nonetheless trumpeted a conclusion that they knew was ...

To the Editor: The investigators in the Global Use of Strategies to Open Occluded Coronary Arteries (GUSTO III) trial (Oct. 16 issue)¹ make an important comparison between reteplase and alteplase, but their investigation has a serious flaw — namely, the ...

To the Editor: Kupfer and Tessler (Oct. 23 issue)¹ report a possible association of ticlopidine with fatal thrombotic thrombocytopenic purpura in two patients, but they imply that platelet transfusion is standard therapy for thrombotic thrombocytopenic ...

To the Editor: Recently, the pathologic process underlying nonsyndromic forms of inherited hearing impairment has been studied at the molecular level.¹ The previously localized DFNA3 and DFNB1 loci, which are associated with nonsyndromic deafness of ...

To the Editor: Perhaps the study by Izbicki et al. (Oct. 23 issue)¹ on immunohistochemical identification of tumor deposits in lymph nodes from patients with esophageal cancer is of value, but since I can't interpret the published photomicrographs I can'...

Reproductive Endocrinology, Surgery, and Technology is a two-volume work consisting of 2399 pages. There are three editors and over 190 contributing authors. From my own experience of editing a book less than one tenth the size of this one, I realize that ...

In recent years, the number of publications in the field of diabetes has increased considerably. More and more original and review articles are published, not only in scientific journals but also in magazines and newspapers. The media, especially ...

Over the past two decades the field of bone biology has expanded rapidly and exponentially. This remarkable growth is due to a large extent to the development of tools that allow an understanding of the fundamental molecular and cellular mechanisms ...

Obesity Review Article, N Engl J Med 1997:337;396-407.. On page 400, in Table 2, under the heading “Human Homologue,” lines 2, 3, and 4 should have read, “1p31,” “4q32(?),” and “11p15,” not “1p32,” “11p15,” and “4q32(?),” as printed.

Screening for Gestational Diabetes Mellitus Editorial, N Engl J Med 1997:337;1625-1626.. On page 1626, the sentence that begins 11 lines from the bottom of the left-hand column should have read, “One interesting finding is that parity is not an ...