The incidence of the sudden infant death syndrome (SIDS) has recently declined.¹ This trend followed the identification of several behavioral risk factors and their subsequent modification through public-education campaigns.² Nonetheless, SIDS remains the ...

Most studies of the prognosis of epilepsy focus on short-term remission of seizures in patients with newly diagnosed epilepsy.¹–⁵ Outcomes after long-term remission of seizures have been reported in well-designed retrospective studies in Minnesota, Sweden,...

Many parents think that their child is dying when he or she has a febrile convulsion,¹ and they are concerned that epilepsy or mental retardation may result. Febrile convulsions are common, occurring in 2 to 4 percent of children at least once before five ...

Normal pubertal development and fertility depend on the intricate interplay of hypothalamic, pituitary, and gonadal factors. Crucial in this respect are normal secretory patterns of follicle-stimulating hormone and luteinizing hormone. These hormones ...

Figure 1. A hookworm larva was acquired by a 47-year-old man during a vacation at a beach on the Alabama coast of the Gulf of Mexico. An isolated lesion resulted, and it resolved after liquid-nitrogen cryotherapy was administered just beyond the advancing ...

Since the early 1980s, homelessness has been an intractable problem in the nation's largest cities. Some observers trace the growth of homelessness largely to the social policies of the 1970s, including the deinstitutionalization of the mentally ill and ...

A primary goal in organ transplantation is the prevention or effective treatment of infection, the most common life-threatening complication of long-term immunosuppressive therapy. The challenges involved in achieving this goal are several: a broad range ...

Presentation of Case

A 54-day-old girl was admitted to the hospital because of recurrent respiratory distress and failure to gain weight.

She had been born to a 38-year-old woman (gravida 2, para 0) who had group B, Rh-positive blood. The mother was ...

The unexpected and unexplained death of an infant is a tragic occurrence. When the infant is less than one year of age and the cause remains unknown despite a thorough investigation including a complete autopsy, examination of the death scene, and review ...

Robert Frost once described home as “the place where, when you have to go there, /They have to take you in.”¹ This is precisely what the homeless lack: not only a home of their own but also a claim on anyone else — kin, community, or government — to take ...

Presentation of Case

A 32-year-old man presented with fever and pain in the right upper quadrant. The patient had been well until the day after a night of heavy alcohol consumption (12 pints of wine¹,²), when fatigue and generalized aches developed. The ...

To the Editor: I am disappointed by and take serious exception to the views you and Dr. Rosenthal express in your editorial on whether human cloning research should be off limits (March 26 issue).¹ I suppose that in contemporary medical journalism, it is ...

To the Editor: Vento et al. (Jan. 29 issue)¹ reported 27 cases of acute hepatitis A among 595 patients with chronic liver disease who were positive for hepatitis B surface antigen (HBsAg) or hepatitis C virus (HCV). Of the 17 patients with acute viral ...

To the Editor: The study by McLaughlin et al. (Jan. 29 issue)¹ implies that hypertensive pulmonary arteries develop beneficial structural changes after prolonged treatment with prostacyclin in patients with primary pulmonary hypertension. Since marked ...

To the Editor: From May 1993 through February 1998, the Food and Drug Administration (FDA) received reports of 43 patients in the United States who had spinal or epidural hematoma or bleeding after receiving the low-molecular-weight heparin enoxaparin (...

To the Editor: Evans et al. (Jan. 22 issue)¹ have developed an innovative computer-assisted management program for antiinfective agents, but they have compared three groups that are not comparable: a group in which the recommendations of the computer-...

To the Editor: Forty-two patients infected with human immunodeficiency virus type 1 (HIV-1) (38 men and 4 women) presented with paronychia of the great toes during the period from September 1996 to September 1997. The median age of the patients was 36 ...

Salisbury. His passion is so ripe it needs must break.

Pembroke. And when it breaks, I fear will issue thence

The foul corruption of a sweet child's death.

(Shakespeare. King John, Act IV, Scene 2, Lines 79–81.)

So starts the 1961 Journal article “...

During the first three decades after World War II, a nationwide system of blood banks was established to meet an ever-growing demand for blood transfusions, and blood bankers were discovering numerous red-cell antigens and developing methods to ensure the ...

With more than 20,000 kidney transplantations performed yearly and more than 150,000 patients alive with a functioning kidney transplant each worldwide, renal transplantation is nowadays a major activity for many nephrologists and transplant surgeons. ...

The supply of donor organs is the Achilles' heel of transplantation. Although the disparities among need, demand, and supply are often discussed, they are rarely understood. For example, each year well over 120,000 people in the United States could ...

An Outbreak Involving Extensive Transmission of a Virulent Strain of Mycobacterium tuberculosis Original Article, N Engl J Med 1998:338;633-639.. On page 633, in the Results paragraph of the Abstract, the sentence that begins on line 8 should have read, “...