Transplantation of hematopoietic stem cells from HLA-identical siblings can be curative in several nonmalignant hematologic disorders, including aplastic anemia, β-thalassemia major, congenital immunodeficiency disorders, and certain inborn errors of ...

Disseminated Mycobacterium avium complex infection is the most common opportunistic bacterial infection in adults infected with the human immunodeficiency virus (HIV).¹,² It has an annual incidence of approximately 20 percent after the occurrence of a ...

Disseminated infection with Mycobacterium avium complex is the most common systemic bacterial infection in advanced stages of the acquired immunodeficiency syndrome (AIDS), occurring in up to 40 percent of patients,¹ and its incidence appears to be ...

Unless they receive antimycobacterial prophylaxis in some form, up to 40 percent of patients have disseminated Mycobacterium avium complex infection within two years of the diagnosis of the acquired immunodeficiency syndrome (AIDS).¹,² Disseminated M. ...

Figure 1. A 16-year-old wrestler had thickened neocartilage in his ear as a result of several untreated auricular hematomas. He presented with a recurrent hematoma that had been drained two days earlier in the emergency department. Panel A shows a ...

China's economic reforms have been in place for almost two decades. First initiated in rural areas in 1978, the reforms have now been implemented nationwide in order to transform the economy to a free-market system. The overall successes of these reforms ...

Since the 1950s more than 80 models of prosthetic heart valves have been developed and used. More than 60,000 valve replacements are performed annually in the United States. Prosthetic heart valves may be mechanical or bioprosthetic. Mechanical valves, ...

Presentation of Case

A 54-year-old woman was admitted to the hospital because of radiologic evidence of pulmonary abnormalities.

The patient had been well until one year earlier, when she began to have a dry cough and mild exertional dyspnea. The cough ...

The clinical complications of sickle cell anemia reflect the vascular damage caused by the abnormal red cells. Filled with hemoglobin S, sickle red cells obstruct and injure vessels when the abnormal hemoglobin polymerizes, is denatured, and releases ...

Mycobacterium avium complex disease is the third most common opportunistic disease affecting patients with AIDS. In a nationwide survey, it occurred in 22 percent of such patients¹; only Pneumocystis carinii pneumonia and Kaposi's sarcoma were more ...

Recent experience in China helps to answer a global question: Does economic development necessarily improve health status, nutrition, and health care? In the late 1950s, when China was a very poor nation, it developed an innovative system of medical care. ...

When I was in California a few weeks ago I discovered how to win a new interactive medical computer game. It works every time. In the game, a variant of SimCity, which is used in schools across the country, you are the president and chief executive ...

To the Editor: Dr. Hasan's statements in his Sounding Board article, “Let's End the Nonprofit Charade” (April 18 issue),¹ provide a disturbing if eloquent example of the mind-set of corporate leaders in the for-profit sector of the American health care ...

To the Editor: In reply to the Sounding Board article by Nudelman and Andrews (April 18 issue),¹ I would point out, first, that to remain competitive in the current market environment, for-profit health plans must provide access to high-quality medical ...

This book reflects the experience of the Child Abuse Team at Cook County Hospital and the Office of the Medical Examiner of Cook County. In the preface the authors highlight the increased incidence of child abuse and estimate that more than three children ...

Multiple pregnancies are on the rise. They now account for about 2 percent of all deliveries, up from 1 percent a decade ago. The principal reason for this increase is indisputable. Advances in the induction of ovulation and assisted reproductive ...

Marsh and Ronner look at 300 years of infertility in America from the vantage point of the late 20th century, with its advanced reproductive techniques. This very personal book evaluates the cultural, social, scientific, and medical aspects of ...

More than 6000 liver transplantations are performed annually in the United States and Europe, so the subject has now become important in both medicine and surgery and deserving of this truly magnum opus, which weighs 5 lb (2.3 kg) and has 85 chapters with ...

Case Records of the Massachusetts General Hospital (Case 14-1996) Case Records of the Massachusetts General Hospital, N Engl J Med 1996:334;1254-1261.. On page 1256, the arrow in Figure 3 was not placed correctly. The corrected figure appears below.

Columbia/HCA'S drive to increase its market power by purchasing not-for-profit community hospitals has raised thorny questions. Lately, it has also met escalating resistance. Columbia's deals are notable for the speed, secrecy, and legal ingenuity with ...